SLIDE

The SLIDE R package is an implementation of the Single Cell Linkage using Distance Estimation (SLIDE) algorithm (Sen et al), to be used to detect infectious reprogramming of cells in high dimentional flow cytometry data. The package contains one major function, slide(), which does the following: 1. Tells us which protein expression levels are significantly up or downregulated in in infected cells compared to uninfected cells 2. Tests for statistically significant evidence for cellular reprogramming under the infectious condition.

For details see Vignettes.

Here is the CRAN Link